Effect van blootstelling op cellen in het lucht-vloeistofgrensvlak in het kader van het EU-project MACRAMÉ

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Jolanda Vermeulen; Eline Groeneveld; Rob Vandebriel; Veronique de Bruijn, 2026, "Effect van blootstelling op cellen in het lucht-vloeistofgrensvlak in het kader van het EU-project MACRAMÉ", https://doi.org/10.21945/372C9EF5-2A4F-475C-B9CD-AA32DAC4408B, RIVM, V1

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Description	In het kader van het EU-project MACRAME hebben we systemen voor de productie van aerosolen uit geavanceerde materialen onderzocht, evenals de effecten daarvan op een co-cultuurmodel van Calu-3-cellen (humane bronchiale epitheelcellen) en macrofagen die zijn gedifferentieerd uit THP-1-cellen (humane monocyten). Geteste parameters: (1) celviabiliteit (LDH-afgifte), (2) celmetabolisme (WST-1-test), (3) barrièrefunctie (TEER) en (4) cytokineproductie (IL-6, IL-8 en TNF-alfa).
Theme	Science and technology
Keyword	Advanced materials, Aerosol generation, Aerosolgeneratie, Air exposure, Air liquid interface, Deeltjesgrootteverdeling, Fluidizer, Geavanceerde materialen, IL-6, IL-8, LDH, Lucht-vloeistofgrensvlak, Luchtblootstelling, Size distribution, TEER, TNF-alpha, VITROCELL Cloud, VITROCELL powderX, WST-1
License/Data Use Agreement	CC-BY-4.0


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Citation Metadata

Persistent Identifier	doi:10.21945/372C9EF5-2A4F-475C-B9CD-AA32DAC4408B
Publication Date	2026-07-17
Title	Effect van blootstelling op cellen in het lucht-vloeistofgrensvlak in het kader van het EU-project MACRAMÉ
Author	Jolanda Vermeulen (Rijksinstituut voor Volksgezondheid en Milieu) Eline Groeneveld (Rijksinstituut voor Volksgezondheid en Milieu) Rob Vandebriel (Rijksinstituut voor Volksgezondheid en Milieu) - ORCID: https://orcid.org/0000-0001-9140-952X Veronique de Bruijn (Rijksinstituut voor Volksgezondheid en Milieu) - ORCID: https://orcid.org/0000-0003-0248-2309
Point of Contact	Use email button above to contact. VTS.GZB.V&Z.RIVM (RIVM)
Description	In het kader van het EU-project MACRAME hebben we systemen voor de productie van aerosolen uit geavanceerde materialen onderzocht, evenals de effecten daarvan op een co-cultuurmodel van Calu-3-cellen (humane bronchiale epitheelcellen) en macrofagen die zijn gedifferentieerd uit THP-1-cellen (humane monocyten). Geteste parameters: (1) celviabiliteit (LDH-afgifte), (2) celmetabolisme (WST-1-test), (3) barrièrefunctie (TEER) en (4) cytokineproductie (IL-6, IL-8 en TNF-alfa).
Theme	Wetenschap en technologie
Keyword	Advanced materials Aerosol generation Aerosolgeneratie Air exposure Air liquid interface Deeltjesgrootteverdeling Fluidizer Geavanceerde materialen IL-6 IL-8 LDH Lucht-vloeistofgrensvlak Luchtblootstelling Size distribution TEER TNF-alpha VITROCELL Cloud VITROCELL powderX WST-1
Time Period	Start Date: 2022-12-01; End Date: 2025-11-30
Data language	Nederlands
Funding Information	MACRAMÉ has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No. 101092686.
Depositor	Rijksinstituut voor Volksgezondheid en Milieu
Documentation	https://macrame-project.eu/
Dataset Series	MACRAMÉ

Geospatial Metadata

Geographic Coverage	Wereldwijd

RIVM metadata

Modification Date Metadata (Unix time)	1784585209
Availability	1
Metadata identifier	3187cac0-ea90-46b9-ad29-e90aa026d4db
DOI	https://doi.org/10.21945/372C9EF5-2A4F-475C-B9CD-AA32DAC4408B

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Access rights	Openbaar
License	CC-BY-4.0
Terms of Use	Data wordt openbaar gepubliceerd rond 2027-01-01

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